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Wednesday, November 20, 2013

What is the Best Probiotics for Cats


Sadly there are only two probiotics used in veterinary medicine that contain what they say they contain and use correct spelling on the packaging!  See below:

Probiotic
Label organisms
Actual concentrationa (CFU/g)
% of claimb
Correct spelling
Adequate label
Adequate label and contents
A
Bifidobacterium animalis
2 × 109
920
Yes
Yes
Yes
B
Bacterial culture
2 × 107
NA
NA
No
No
C
Mixed lactic acid bacteria, Bacillus subtillus (sic)
1.7 × 104
0.9
No
No
No
D
L. acidophilus, L. casei, Enterococcus faecium, B. subtilus (sic), B. licheniformis, B. coagulins (sic)
1.1 × 108
0.9
No
No
No
E
L. acidophilus, L. casei, Enterococcus faecium, B. subtilus (sic), B. licheniformis, B. coagulins (sic)
2.3 × 106
1.8
No
No
No
F
Bacillus subtilis, Bacillus lichenformis, Lactobacillus
7.2 × 107
NA
Yes
No
No
G
L. acidophilus, L. plantarum, L. brevis, L. rhamnosus, B. bifidus (sic), B. longum
4.8 × 105
NA
No
No
No
H
L. acidophilus, B. thermophilum, B. longum, Enterococcus faecium
2.7 × 107
2.7
Yes
Yes
No
I
Bacillus coagulans (L. sporogenes)
4 × 105
NA
Yes
No
No
J
Probiotics
1 × 104
NA
NA
No
No
K
Lactobacillus acidophilus, Bifidobacterium longum, B. bifidum, B. infantis
1.6 × 107
0.16
Yes
Yes
No
L
Probiotic blend (6 bioactive strains)
1 × 106
2.3
NA
No
No
M
Bacillus subtillis (sic), mixed lactic acid bacteria
2.3 × 106
3194
No
No
No
N
Enterococcus faecium
2.6 × 108
260
Yes
Yes
Yes
O
E. thermophilus, L. acidophilus
5.7 × 108
NA
Yes
No
No
P
L. acidophilus, Bifidobacterium bifidum, B. infantis, B. longum, L. bulgaricus, L. casei, L. salivarius, S. thermophilus
4 × 108
16
Yes
Yes
No
Q
Lactobacillus sporogenes
1 × 109
247
Yes
No
No
R
Bacillus coagulans (L. sporogenes), Bacillus subtilis
6 × 106
NA
Yes
No
No
S
L. acidophilus, B. bifidum, B. infantis, B. longum, L. helveticus, L. casei, L. salivarius, S. thermophilus
3 × 105
NA
Yes
No
No
T
L. acidophilus, B. bifidum, B. infantis, B. longum, L. helveticus, L. casei, L. salivarius
9 × 108
NA
Yes
No
No
U
L. acidophilus
0
0
Yes
Yes
No
V
L. acidophilus, B. longum
3.6 × 109
50
Yes
Yes
No
V
B. bifidum, L. lactic (sic), L. acidophilus
1 ×107
7
No
No
No
X
L. acidophilus, B. bifidum, B. infantis, B. longum, L. casei, L. helveticus, L. plantarum, L. rhamnosus, L. salivarius, L. lactis
3 × 108
38
Yes
Yes
No
Y
Lactobacillus paracasei, L. curvatus, L. rhamnosis (sic), L. plantarum
4.5 × 105
NA
No
No
No
A — Prostora Max, The Iams Company, Cincinnati, Ohio 45202, USA; 
B — Digest-Aide, Canine Herbals, Guelph, Ontario N1H 1E9; 
C — digest-aide, McIntosh ProLine Products Inc, Wheatley, Ontario N0P 2P0; 
D — Holistic Solutions, Eagle Pack Pet Foods Inc, Mishawaka, Indiana 46544, USA; 
E — Holistic Transitions, Eagle Pack Pet Foods Inc, Mishawaka, Indiana 46544, USA; 
F — PROBIOplus, Herbs for Horses, Guelph, Ontario N1H 1E9; 
G — Equine Biotic 8, Omega Alpha Pharmaceuticals Inc, Toronto, Ontario M1L 3K2; 
H — N’Zymes, Biopet Inc, Las Vegas, Nevada 89193-4347, USA; 
I — Geneflora, Cycles of Life, Newbury Park, California 91320, USA; 
J — Seagreens Powder, Holistic Blend, Mississauga, Ontario L5L 6A6; 
K — Rx Biotic, Rx Vitamins Inc, Elmsford, New York 10523, USA; 
L — Rx Nutrigest, Rx Vitamins Inc, Elmsford, New York 10523, USA; 
M — Acute Care Supportive G.I. Powder, Centaur VA Animal Health, Guelph, Ontario N1H 6T9; 
N — FortiFlora, Nestle Purina PetCare Company, Mississauga, Ontario L5J 1K7, USA; 
O — Azodyl, VĂ©toquinol Canada Inc, Lavaltrie, Quebec J5T 3S5; 
P — Probiotic Blend, Only Natural Pet Store, Boulder, Colorado 80301, USA; 
Q — Lactobacillus sporogenes, Thorne Research, Dover, Indiana 83825, USA; 
R — Plant Enzymes & Probiotics, Animal Essentials, Victor, Montana 59875, USA; 
S — Spectra Probiotic, Integrative Therapeutics Inc, Green Bay, Wisconsin 54311, USA; 
T — Blue Heron, Integrative Therapeutics Inc, Green Bay, Wisconsin 54311, USA; 
U — Digestive Support, Pet Naturals of Vermont, Essex Junction, Vermont 05453, USA; 
V — Probiotic Pearls, Integrative Therapeutics Inc, Green Bay, Wisconsin 54311, USA; 
W — Pet Inoculant, Wysong Corporation, Midland, Michigan 48642-7779, USA; 
X — Total Biotics Powder, Ultra-Pet Products LLC, Laguna Hills, California 92653, USA; 
Y — Living Pet Probiotic, Living Streams Mission, Coeur D-Alene, Idaho 83815, USA.
aTotal numbers of all organisms.
bPercentage of label claim calculated as actual concentration (CFU/g)/label claim (CFU/g) × 100. NA — Not available — Unable to calculate percentage since label did not contain an expected number of viable organisms.

Monday, March 25, 2013

Taking Blood Pressure in Cats


Taking blood pressure is important in cats when hypertension is suspected.  We use the Parks's Doppler unit which is the most accurate doppler for cats.  The Doppler method uses a piezoelectric crystal (within the probe) that emits ultrasound waves to detect an arterial pulse. Once the pulse has been detected an inflatable cuff (sphygmomanometer) is inflated proximal to the probe to occlude the artery (Figure 1). This cuff is gradually deflated and the pressure in the cuff during this period is monitored. The pressure to which the cuff is deflated when the pulse is first detected again represents systolic blood pressure.

Monday, January 28, 2013

Calcitriol for Use in Cats with Kidney Issues


Calcitriol (Rocaltrol)


Background
Calcitriol is mostly used in the treatment of chronic kidney failure although it can also be used in hypocalcemia (low blood calcium). The relationship between calcitriol (active Vitamin D) and parathyroid hormone is somewhat complicated but it is not possible to understand the function of this medication without some understanding of the system.
Calcitriol and 1,25 dihydroxycholecalciferol are both scientific names for active vitamin D. The biochemistry of vitamin D is very different from that of other vitamins because vitamin D is actually a hormone. To understand how calcitriol is helpful therapeutically, the following offers some background information about vitamin D, its metabolic opposite parathyroid hormone, and the general calcium and phosphorus balance within the body.
A Review of Vitamin D
The story of vitamin D begins when a vitamin D precursor is eaten. The precursor we get from plants is called ergosterol and the precursor we get from eating animal tissues is called 7- dehydrocholesterol. These substances are absorbed into the body when they are digested and transported to the skin for modification by sunlight radiation (hence the popular terminology of vitamin D as the sunshine vitamin). The animal origin substance is converted to what is called vitamin D3 or cholecalciferol, while the plant substance becomes vitamin D2 or ergocalciferol. From here we will follow the animal origin hormone as it is the most metabolically active.
The next stop is the liver for further modification (a hydroxyl group is added to the 25th carbon of the vitamin D3 molecule) thus forming 25-hydroxycholecalciferol, which is too hard to pronounce and is generally referred to as 25-D3 or calcidiol.
From here, calcidiol circulates to the kidney for its final activation. Another hydroxyl group is added in the final activation to form 1,25 dihydroxycholecalciferol, aka calcitriol.
Actions of Vitamin D and Parathyroid Hormone (PTH)
There are four tiny parathyroid glands around the thyroid gland in the throat area. These glands produce a biochemical called parathyroid hormone, often abbreviated as PTH. When blood calcium drops, PTH is secreted heavily.
Parathyroid hormone encourages the activation of calcidiol into calcitriol by the kidney.
Both PTH and calcitriol act to increase calcium levels by mobilizing calcium from the bones and preventing the kidney from excreting calcium.
PTH may encourage calcitriol activation but calcitriol instructs the parathyroid glands to cut PTH secretion. This means that when there is enough calcitriol, PTH secretion shuts off. This prevents the blood calcium level from increasing out of control.
There is a third hormone called calcitonin that is responsible for excess calcium returning to the bones for storage.

When it comes to phosphorus PTH and calcitriol act as opposites.
Calcitriol acts to have the kidney retain phosphorus while PTH instructs the kidney to dump phosphorus.
page1image35128
page1image35400

These hormones work together to maintain the blood calcium level in a specific range.
What Happens in Kidney Failure?
In early kidney failure, the kidney is not able to activate vitamin D efficiently nor is it able to adequately excrete phosphorus. As a result active vitamin D levels drop (which results in a drop in blood calcium) and blood phosphate levels start to climb. The calcium drop is seen by the parathyroid gland, PTH is released, and hopefully the situation can be normalized.
But the kidney may not have enough capacity to activate vitamin D no matter how much PTH is circulating. More and more PTH is desperately secreted to get some vitamin D activated and to get the excess phosphorus dumped. The kidney simply cannot respond. Soon there is so much circulating phosphate that it begins to combine with the blood calcium, and calcium phosphate crystals begin to form in the body’s soft tissues (which, of course, further lowers blood calcium levels). This removal of calcium from the circulation causes the bones to release all available calcium in an attempt to maintain a normal blood calcium level. The bones becomes soft and bendable (this is classically most notable in the jaws, leading to the condition in advanced kidney failure called rubber jaw.) The bone crystals in the soft tissues generate an inflammatory response. None of the tissues involved can function normally. A metabolic disaster has occurred.
How this Medication is Used
By giving active vitamin D in pill or liquid form, the above disaster can hopefully be averted or reversed. (It is more easily averted than reversed.) It has been established that PTH is an important toxin in kidney failure and we want to reduce its secretion. This is best done with minute (measured in units 1000 times smaller than the usual dosages) quantities of vitamin D. These quantities are enough to shut off PTH secretion but are not high enough to lead to elevated phosphorus levels.
If calcitriol is started early in kidney failure, parathyroid levels may be kept low enough that calcium/phosphorus imbalance never becomes an issue. If it is started later in failure, it is helpful but may not be able to provide as good a response.
Recently a survey of the owners and veterinarians of nearly 2000 pets in chronic renal failure was taken. The animals all received calcitriol. Approximately 80% of the owners reported that their pets were brighter and more social and had better appetites on calcitriol. It was also felt that these animals had a substantially longer life span than patients not receiving calcitriol.
Side Effects
If calcitriol elevates serum calcium levels, this can lead to calcium precipitation in the kidneys, making kidney damage worse. Calcitriol cannot be given to patients with elevated serum calcium levels, and monitoring is necessary to make sure serum calcium levels do not rise.
Interactions with other Drugs
Phosphate binders are common in the treatment of kidney disease. If the binder in use contains calcium, elevated blood calcium levels could become a concern.
Cautions and Concerns
Calcitriol cannot be used in patients that have an elevated (greater than 6 mg/dl) plasma phosphorus level. Calcitriol might elevate phosphorus further at this stage, which is exactly what we do not want. In such patients, plasma phosphorus must be reduced by diet, fluid administration, or by phosphate binders before calcitriol can be started.
It is helpful to monitor PTH levels in patients on calcitriol therapy as some dosage adjustment is sometimes beneficial depending on the PTH level. This kind of monitoring is not crucial to calcitriol use, however.
Calcitriol can be given with or without food.
Compounding pharmacies are needed to create an oral liquid or capsule in a size beneficial to the individual patient. A commercial vitamin D supplement is not useful (most over the counter formulas include ergocalciferol that the diseased kidney cannot activate, and manufactured doses of the prescription product are too high).

Wednesday, June 20, 2012

Perfect Litter Boxes





Thursday, June 14, 2012


Help for Feline Aggression

  • Stop doing the things that trigger the cat.  For example, for cats with petting aggression, don’t pet them.  You can often recognize body signs that cats show when they start to become annoyed.  Their eyes narrow, their ears swivel sideways, they look over their shoulder at the culprit, and their tails twitch.
  • Teach the cat to obey a command using the clicker method which is conditionally rewarded with a treat.   
http://www.youtube.com/watch?v=q787R2DNDJI
The following video is for clicker training your cat to go to a mat but you could use the same technique to train your cat to go to another room (say for example when she is showing signs of aggression).
  • Exercise!  Spend at least 15 minutes twice a day exercising the cat with a favorite toy, such as a laser light or feather wand.


Monday, May 7, 2012

Cat Food


Domestic cats originated from the Middle East.  They ate small prey such as birds, mice, rabbits, lizards, and bugs.  They did not eat seafood or larger animals such as cattle or venison. Cats are obligate carnivores, meaning that they require a meat diet in order to sustain their nutritional needs. The ability to synthetically produce nutrients such as taurine has allowed the pet food industry to make cat foods that are high in plant matter instead of meat. We believe this has led to a high incidence of health problems in cats including inflammatory bowel disease, pancreatitis, and diabetes.
The following ingredients have been known to cause a considerable amount of intestinal inflammation in cats:
Wheat 
Soy 
Corn 
Beef 
Lamb 
Seafood
We recommend that cats eat poultry or rabbit because it is similar to what they would eat in the wild. Canned food is thought to be more healthy than dry due to the fact that it is almost always lower in carbohydrates and higher in protein and moisture. A diet consisting of canned food only is more healthy for cats, but due to the fact that we all have busy schedules, it may be more convenient to feed some dry and some canned. In addition, some cats are dry food addicts and will not switch to canned food.
Generally cats should eat between 160 to 200 calories daily. As a rule of thumb, canned foods contain about 30 calories per ounce. Dry foods vary from 300 to 600 calories per cup. You can often find the exact caloric content of a particular food on the packaging or online.
Recommended Canned Foods:
Instinct Chicken Formula (pate)
Instinct Duck Formula (pate)
Evo 95% Chicken and Turkey (pate)
Wellness Core Chicken Formula (pate)
Wellness Core Turkey Formula (pate)
There are also Wellness Core cubed and minced meat for cats that don’t like pates.
Before Grain Chicken (pate)
Before Grain Turkey (pate)
Before Grain Quail and Chicken (pate)
Homestyle Duck and Chicken Stew (meat in gravy)
Homestyle Turkey and Liver Stew (meat in gravy)
The dry foods that we recommend contain less than 10% carbs, and more than 45% protein.
Recommended Dry Foods:
Evo Turkey and Chicken Formula 603 cal / cup 
GO Chicken/Turkey/Duck 473 cal / cup
Many people feed raw diets to their cats. We do not recommend feeding only raw, but rather feeding a variety of canned and raw due to the fact that few studies have been done to ensure that raw foods contain the required nutrients for cats. There is also a risk that raw foods contain bacteria such as salmonella and E. Coli so handling it properly when feeding it is important. Instinct by Nature’s Variety does pressure pasteurize their raw food so it may be safer.
Recommended Raw Foods:
Chicken Formula - Instinct Raw Frozen Diet 
Organic Chicken Formula - Instinct Raw Frozen Diet


Tuesday, September 27, 2011

10 Signs of Illness in Cats












1Inappropriate elimination A cat that urinates inappropri- ately could have any number of conditions associated with the behavior, including lower urinary tract disease, kidney disease, uri- nary tract infection, and diabetes mellitus. It can also be a sign of arthritis, which makes it difficult for cats to get into the litter box.
2Changes in interaction Cats are social animals, so changes in interactions with humans or pets can signal disease, fear, anxiety, or pain.
3Changes in activity
A decrease in activity is often a sign of arthritis or systemic illness, while an increase in activity can be caused by hyperthyroidism.
4Changes in sleeping habits
If your cat is sleeping more than normal (keep in mind that average adult cats may sleep 16 to 18 hours a day—though much of that is “catnapping”), it could be a sign of an underlying disease.
5Changes in food and water consumption Most cats are not finicky eaters. Decreased food intake can be a sign of several disorders, ranging from poor dental health to cancer. Increased food consumption can be caused by diabetes mellitus, hyperthyroidism, or other health problems.
6Unexplained weight loss or gain Sudden weight loss can be a sign of hyperthyroidism, diabe- tes mellitus, or a host of other diseases. Obesity, on the other hand, can cause an increased risk of diabetes mellitus, joint disease, and other problems.
7
Changes in
grooming
Patches of hair loss or a greasy or matted appearance can signal an underlying disease. Cats who
have difficulty grooming often suffer from fear, anxi- ety, obesity, or other illnesses. An increase in groom- ing may signal a skin problem.
8
Signs of stress
Stressed cats may exhibit signs of depression,
hide more, or spend more time awake and scanning their environment. These signs may indicate a medi- cal condition, so it’s important to rule out physical ailments before addressing the stress behaviorally.
9
Changes in vocalization
An increase in vocalization or howling is often
seen with an underlying condition like hyperthyroid- ism or high blood pressure. Many cats also vocalize more if they’re in pain or anxious.
10
Bad breath
Bad breath is an early indicator of an oral problem—studies have shown that 70 percent of cats have gum disease as early as age 3.

Adapted from healthycatsforlife.com and Dr. Susan Little, DABVP (feline), Bytown Cat Hospital in Ottawa, Ontario